Skip directly to searchSkip directly to the site navigationSkip directly to the page's main content

Health Indicator Report of Birth Defects: Prevalence of Trisomy 21 (Down Syndrome) per 10,000 Live Births

Birth defects pose a significant public health problem. One in 33 babies is born with a structural birth defect in the United States. Birth defects are a leading cause of infant mortality and responsible for considerable morbidity with enormous economic and social costs. Usually, mental development and physical development are slower in people with Down syndrome than in those without it. Babies and adults with Down syndrome can have physical problems, as well as intellectual disabilities. Some physical problems associated with Down syndrome include: -A birth defect of the heart -Stomach problems, such as a blocked small intestine -Celiac disease, a digestive disease that damages the small intestine so that nutrients from food are not absorbed well -Problems with memory, concentration, and judgment, often called dementia -Hearing problems -Eye problems, such as cataracts or trouble seeing objects that are close by (far-sighted) -Thyroid problems -Skeletal problems A person with Down syndrome can have an IQ in the mild-to-moderate range of intellectual disabilities. He or she also might have delayed language development and difficulties with physical coordination.

Down Syndrome Births to Mothers Over Age 35 at Delivery by County 2006-2011


Notes

New Mexico live-born infants with Down syndrome, 2006-2011. The following International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) codes were used to identify Down syndrome: 758.0. In 1987, CDC put forth a set of 6 digit codes (the sixth digit provides greater specificity for diagnosis) based on the British Pediatric Association Classification of Diseases and the ICD-9-CM. If CDC/BPA codes are present, the following were used to identify Down syndrome: 758.000 - 740.090.

Data Interpretation Issues

In January 2000, birth defects became a reportable condition in New Mexico; however, birth defects were collected prior to this date. The first year of consistent data is 1998. However, data for Down syndrome were not collected consistently until 2004. For Down syndrome data, the most recent year of analyzed data is 2011. Data are collected on live births occurring in-state to NM residents. Therefore, live births that occur in NM among out-of-state residents are excluded. Case finding/identification occurs through review of birth and death certificates, hospital discharge diagnoses, records from pediatric specialists and prenatal diagnostic providers. Birth defect cases are ascertained up to age 4; however, the majority of diagnoses are made by age 1.

Definition

Down syndrome is a condition in which a baby is born with an extra chromosome. Chromosomes are small "packages" of genes in the body. They determine how a baby's body forms during pregnancy and how, as the baby grows in the womb and after birth, the baby's body functions. Normally, a baby is born with 46 chromosomes. Babies born with Down syndrome have an extra copy of one of these chromosomes. This extra copy changes the body's and brain's development and causes mental and physical problems for the baby. Prevalence of Down syndrome is calculated in two ways: 1) the number of live-born infants with Down syndrome to mothers less than 35 years of age per 10,000 live-born infants and 2) the number of live-born infants with Down syndrome to mothers 35 years of age or older per 10,000 live-born infants. (Live-born infants are the infants born with any evidence of life).

Numerator

Number of live-born infants with Down syndrome to mothers in a given age group at delivery.

Denominator

Total number of live-born infants to mothers in a given age group at delivery.

How Do We Compare With the U.S.?

The national prevalence of Down syndrome among births from 2004-2006 is 14.47 per 10,000 births (adjusted for maternal age). These data come from 14 birth defects surveillance programs: Arkansas, Arizona, California [8-county Central Valley], Colorado, Georgia [5-county metropolitan Atlanta], Illinois, Iowa, Kentucky, Massachusetts, North Carolina, Oklahoma, Puerto Rico, Texas, and Utah. For more information, please see: http://www.cdc.gov/ncbddd/features/birthdefects-keyfindings.html

Page Content Updated On 07/31/2014, Published on 07/31/2014
The NM EPHT website is supported by Cooperative Agreement Number, 6 NUE1EH001354 (previously, 5 U38EH000949), funded by the Centers for Disease Control and Prevention (CDC). Its contents are solely the responsibility of the authors and do not necessarily represent the official views of CDC or do not necessarily reflect the official policies of the Department of Health and Human Services, nor does the mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. The information published on this website may be reproduced without permission. Please use the following citation: " Retrieved Tue, 18 June 2019 4:50:15 from New Mexico EPHT Tracking Public Web site: https://nmtracking.org/ ".

Content updated: Fri, 5 Sep 2014 13:06:56 MDT